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Senior Research Scientist Job

Read the Senior Research Scientist (job description) to understand the position requirements.



    Hands-on technical leadership of all aspects of purification process development, implementation GMP manufacturing support. Manages mentors research associates members of project teams in initiation execution of laboratory experimentation, considering appropriate safety, economic regulatory factors. Works under challenging settings timelines where data requires critical evaluation, sometimes employing use of ingenuity creativity.
    A strong understanding of purification process development for early late stage protein therapeutics is required. The successful applicant will demonstrate technical proficiency, scientific creativity collaboration with others team members departments. The applicant will be expected to demonstrate leadership in laboratory, oversee delegate experimental/project responsibilities, independently champion technology development projects, be involved in new product evaluation and also definition implementation of purification process platforms. The applicant is expected to design execute experiments supporting process definition, optimization and, validation/characterization and also support Technical Operations in scale-up process transfer activities.
    The applicant will support process transfers from development to clinical commercial GMP manufacturing, including definition of bill of materials, batch record drafting/review discrepancy resolution. The applicant will also serve as process development representative during purification operations, provide technical trouble-shooting identify opportunities for future process equipment improvements. The applicant may be expected to travel to support tech transfer manufacture operations.
    The applicant will author, review approve development reports, process descriptions, batch records, regulatory filings process validation characterization reports. The applicant must demonstrate excellent verbal technical writing skills.
    The ideal applicant has a strong understanding of purification process operations: centrifugation, normal flow filtration, chromatography operations, tangential flow filtration virus inactivation/removal is required.
    The applicant should be self-motivated organized, familiar with relevant literature enjoy scientific investigation thinking. The applicant must think critically creativity be able to work independently, define appropriate resources for resolution of problems have strong prioritization planning skills. Makes key insights decisions to direct projects with sometimes minimal data if necessary ensure project timelines are met delivered.
    The applicant should be an effective communicator of ideas is successful presenting technical solutions has ability to influence project teams. Proactively presents results of work, interprets data draws conclusions regarding presented material. The ability to proactively efficiently identify current or future issues successfully develop solutions in a collaborative multidisciplinary environment is crucial.
    Excellent management leadership skills. The ability to motivate, inspire develop research associates is required.
    Serve as a purification sub-team functional lead on CMC. Applicant will be highly proactive, collaborative engage in technical discussions communicate potential issues, solutions, timelines deliverables.
    Responsible accountable for developing biologics processes for manufacturing of drug substances.
    Hands-on familiarity with Pilot Plant operations in collaboration with Technical Operations group. Able to write master batch records development summaries independently.
    Reporting to department Director, advance development of economical, state-of-the-art techniques to isolate, purify characterize biologic projects in early late stage.
    Working independently, plans designs, implements analyzes laboratory experimentation to advance scientific knowledge of drug substances or techniques to identify such substances with limited supervision.
    Advises influences members of project teams in initiation execution of laboratory experimentation, considering various factors.
    Maintains full working knowledge of principles theories, applying such knowledge to direction that supports Company interests.
    Demonstrates ability in developing purification methods, techniques evaluation criteria for obtaining results interpreting experimental outcomes.
    Make contributions to scientific literature conferences through publication presentation of research results.
    Writes executes project plans coordinates team, sub-team, or self to make sure deliverables are met.
    Demonstrates excellent communication skills (both verbal technical) strong interpersonal skills.
    Demonstrates collaborative communication problem solving spirit.
    7 experience years PhD in a relevant scientific discipline.
    BS or MS degree with extensive industry experience.


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